GERD / Acid refluxHeartburnPeptic (gastric & duodenal) ulcersH. pylori–associated ulcers (used with antibiotics)Erosive esophagitisPreventing ulcers in patients taking NSAIDs long-termZollinger–Ellison syndrome (excess acid production)Chronic gastritis and dyspepsia
Contraindications:
Avoid use in:Known allergy to Esomeprazole, omeprazole, or other PPIsSevere liver disease (dose adjustment needed)Combination with certain drugs (risk of interactions):Clopidogrel (reduces its effect)Nelfinavir (antiviral)Rilpivirine, warfarin (needs caution)
Side Effects:
CommonHeadacheNausea, vomitingDiarrhea or constipationGas / bloatingStomach discomfortDry mouthDizzinessLess commonJoint or muscle painVitamin B12 deficiency (long-term use)Low magnesium (prolonged use)
Precautions:
Take on an empty stomach, 30 minutes before breakfast.Do not crush or chew the tablet.Long-term use (>3–6 months) should be monitored due to risk of:Vitamin B12 deficiencyLow magnesiumCalcium deficiencyUse cautiously in kidney diseaseAvoid in patients on clopidogrel unless advisedPregnant or breastfeeding women should consult a doctor.
Dietary Restrictions:
Avoid / LimitSpicy, oily, fried foodsExcess tea/coffeeCitrus fruits if they worsen symptomsTomato-based foodsSodas and carbonated drinksAlcoholChocolateLate-night mealsRecommendedEat small, frequent mealsAvoid lying down 2–3 hours after mealsMaintain healthy weightDrink plenty of water
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